购物车
- 全部删除
- 您的购物车当前为空
Gadolinium chloride 是特殊的钙敏感受体激动剂,可用于研究心血管疾病。
Gadolinium chloride 是特殊的钙敏感受体激动剂,可用于研究心血管疾病。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 327 | 现货 | |
50 mg | ¥ 460 | 现货 | |
100 mg | ¥ 756 | 现货 | |
500 mg | ¥ 1,668 | 现货 |
产品描述 | Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist |
体外活性 | Gadolinium chloride (GdCl ) , a well-known Kupffer/foam cell inhibitor, at late stages of NPC liver disease and compared it with NPC1 genetic rescue in hepatocytes in vivo.?GdCl treatment successfully blocked the endocytic capacity of hepatic Kupffer/foam measured by India ink endocytosis, decreased the levels CD68-A marker of Kupffer cells in the liver-and normalized the transaminase levels in serum of NPC mice to a similar extent to those obtained by genetic Npc1 rescue of liver cells.?Gadolinium salts are widely used as magnetic resonance imaging (MRI) contrasts.?This study opens the possibility of targeting foam cells with gadolinium or by other means for improving NPC liver disease.?Synopsis: Gadolinium chloride can effectively rescue some parameters of liver dysfunction in NPC mice and its potential use in patients should be carefully evaluated. |
别名 | 氯化钆 |
分子量 | 263.61 |
分子式 | Cl3Gd |
CAS No. | 10138-52-0 |
Smiles | [Gd](Cl)(Cl)Cl |
密度 | 4.52 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | DMSO: 7.5 mg/mL (28.45 mM), Sonication is recommended. H2O: 9.85 mg/mL | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
|
版权所有©2015-2024 TargetMol Chemicals Inc.保留所有权利.
评论内容